#ADC SERVICES ADC DESIGN, OPTIMIZATION AND TROUBLESHOOTING
“ADC DESIGN
1. ADC technology makes it possible to take compounds with potency, pharmacodynamic and pharmacokinetic problems. WASSC’s Technologies platform makes it possible to take these compounds and turn them into an ADC by optimizing the linker, the antibody and the complex itself.
2. Our WASSC technology enables the synthesis of homogeneous ADCs, making them more predictable and reproducible. Since the conjugation site has an impact on the biochemical properties of the ADCs, it is possible to avoid problems associated with it. This technology does not involve genetic engineering, and therefore preserves the integrity of the antibody.
3. The ADC platform also enables targeted delivery of cargo (toxic molecules, peptides, etc.) to cancer cells or cells overexpressing certain receptors.
“TROUBLESHOOTING AND OPTIMIZATION
4. Issues to be addressed: conjugation, DAR, pharmacokinetics and pharmacodynamics of ADC, Linker, drug delivery mechanism versus compound alone.
“ADC DESIGN
1. ADC technology makes it possible to take compounds with potency, pharmaco dynamic and pharmaco kinetic problems. WASSC’s Technologies platform makes it possible to take these compounds and turn them into an ADC by optimizing the linker, the antibody and the complex itself.
2. Our WASSC technology enables the synthesis of homogeneous ADCs, making them more predictable and reproducible. Since the conjugation site has an impact on the biochemical properties of the ADCs, it is possible to avoid problems associated with it. This technology does not involve genetic engineering, and therefore preserves the integrity of the antibody.
3. The ADC platform also enables targeted delivery of cargo (toxic molecules, peptides, etc.) to cancer cells or cells overexpressing certain receptors.
“TROUBLESHOOT
4. Issues to be addressed: conjugation, DAR, pharmaco kinetics and pharmaco dynamics of ADC, Linker, drug delivery mechanism versus compound alone.
“OPTIMIZATION
5. Issues to be addressed: conjugation, DAR, pharmaco kinetics and pharmaco dynamics of ADC, Linker, drug delivery mechanism versus compound alone
“WASSC'S platforms are the solution to optimize your bioactive molecules & solve your issues
#1 wassc's ACCELERATE
WASSC’S Accelerate the development of innovative treatment by offering a unique opportunity to produce the next generation of ADC and Vaccine by using its bioconjugation screening platform and drug/linker design platform.
#2 wassc's DEVELOP
WASSC’S Develop new delivery system based on simplest and tunable nanoemulsion system and hydrogel technologies useful for topic, oral and other administration mode.
#3 wassc's CREATE
WASSC’S Create a multidisciplinary team built with different expertise and experiences that allow us to approach science in a different way to obtain the most out of each project
